Dr. Emilianne Limbrick

Dr. Emilianne Limbrick is a Mercer University alumna who graduated with a Bachelor of Science in biochemistry and molecular biology in 2010. After completing her Ph.D. in chemistry at Vanderbilt University, she returned to Mercer and joined the faculty in 2016.

Education

• Ph.D., Vanderbilt University
• B.S., Mercer University

Specialty

Biochemistry and natural product biosynthesis

Professional Interests

Dr. Limbrick teaches general chemistry I and II, biochemistry I, biochemistry I lab, and biochemistry and molecular biology capstone lab. Her research focuses on the biosynthesis of secondary metabolites in bacteria. Undergraduate researchers in her lab learn techniques that intersect the fields of chemistry, biochemistry, and molecular biology as they explore how bacteria make complex molecules.

Other Interests

Outside of Mercer, Dr. Limbrick enjoys spending time with her husband, sons, and pets (a dog, a cat, chickens, and fish). She loves gardening and DIY projects of all sorts.

Recent Publications

• Kittrell CG, Shah SC, Halbert ME, Scott DH, Limbrick EM. Genomic analysis suggests Salinispora is a rich source of novel lanthipeptides. Mol Genet Genomics. 2020 Nov;295(6):1529-1535. doi: 10.1007/s00438-020-01718-1. Epub 2020 Sep 7. PMID: 32894358.
• Limbrick EM, Graf M, Derewacz DK, Nguyen F, Spraggins JM, Wieland M, Ynigez-Gutierrez AE, Reisman BJ, Zinshteyn B, McCulloch KM, Iverson TM, Green R, Wilson DN, Bachmann BO. Bifunctional Nitrone-Conjugated Secondary Metabolite Targeting the Ribosome. J Am Chem Soc. 2020 Oct 28;142(43):18369-18377. doi: 10.1021/jacs.0c04675. Epub 2020 Oct 19. PMID: 32709196; PMCID: PMC8129991.
• Limbrick EM, Yñigez-Gutierrez AE, Dulin CC, Derewacz DK, Spraggins JM, McCulloch KM, Iverson TM, Bachmann BO. Methyltransferase Contingencies in the Pathway of Everninomicin D Antibiotics and Analogues. Chembiochem. 2020 Dec 1;21(23):3349-3358. doi: 10.1002/cbic.202000305. Epub 2020 Sep 7. PMID: 32686210.
• Starbird CA, Perry NA, Chen Q, Berndt S, Yamakawa I, Loukachevitch LV, Limbrick EM, Bachmann BO, Iverson TM, McCulloch KM. The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains. Biochemistry. 2018 Dec 18;57(50):6827-6837. doi: 10.1021/acs.biochem.8b00836. Epub 2018 Dec 7. PMID: 30525509; PMCID: PMC7231510.

Contact Dr. Emilianne Limbrick

(478) 301-2346
limbrick_em@mercer.edu
Office: Godsey Science Center, Room 433